NCT06753409 Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery
| NCT ID | NCT06753409 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Assiut University |
| Condition | Postoperative Acute Kidney Injury |
| Study Type | INTERVENTIONAL |
| Enrollment | 162 participants |
| Start Date | 2025-02-01 |
| Primary Completion | 2026-12-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 162 participants in total. It began in 2025-02-01 with a primary completion date of 2026-12-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).
Eligibility Criteria
Inclusion Criteria: 1. Patients scheduled for major abdominal surgery lasting more than 2 hours under general anesthesia. 2. American Society of Anesthesiologists Physical Status (ASA) score I-III. 3. Age range of 18-70 years. 4. Both male and female patients. Exclusion Criteria: 1. Emergency surgeries. 2. Uncontrolled hypertension (systolic blood pressure \>150 mm Hg) despite medication. 3. Recent acute cardiovascular events, including heart failure or acute coronary syndrome. 4. Chronic kidney disease with a glomerular filtration rate \<30 ml/min/1.73 m² or requiring renal replacement therapy. 5. Severe hepatic failure (ASAT/ALAT \>2N, elevated bilirubin, or PT \<50%). 6. Preoperative sepsis or septic shock. 7. Pregnancy. 8. Patient refusal to participate in the study.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06753409 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Postoperative Acute Kidney Injury. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06753409 currently recruiting?
Yes, NCT06753409 is actively recruiting participants. Contact the research team at walaa95.hamdy@gmail.com for enrollment information.
Where is the NCT06753409 trial being conducted?
This trial is being conducted at Asyut, Egypt.
Who is sponsoring the NCT06753409 clinical trial?
NCT06753409 is sponsored by Assiut University. The trial plans to enroll 162 participants.
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