Trial Parameters
Condition Reproductive Age
Sponsor Jagiellonian University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex FEMALE
Min Age 18 Years
Max Age 45 Years
Start Date 2025-01-20
Completion 2026-06-30
All Conditions
Interventions
Measurement of interleukin-6 (il-6) concentration in blood serumMeasurement of fasting tumor necrosis factor α (TNF-α) concentrationMeasurement of interleukin-18 (il-18) concentration
Brief Summary
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin resistance, women with polycystic ovary syndrome without carbohydrate metabolism disorders, and women without PCOS (control group).
Eligibility Criteria
Inclusion Criteria: * women aged 18-45 years Exclusion Criteria: * previous removal of at least one ovary * treated diabetes of any type * diagnosed and treated metabolic diseases * diagnosed and treated autoimmune diseases * diagnosed and treated autoinflammatory diseases