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Recruiting NCT04772768

NCT04772768 Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease

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Clinical Trial Summary
NCT ID NCT04772768
Status Recruiting
Phase
Sponsor Amsterdam UMC, location VUmc
Condition Recurrent Angina After Coronary Artery Bypass Graft
Study Type OBSERVATIONAL
Enrollment 500 participants
Start Date 2019-08-23
Primary Completion 2024-07-23

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 90 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 500 participants in total. It began in 2019-08-23 with a primary completion date of 2024-07-23.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a multi-center, observational cohort study including patients with prior coronary artery bypass grafting (CABG) and ≥1 saphenous vein grafts (SVG) presenting with recurrent ischemic symptoms. Objective: to investigate the clinical outcomes in patients with prior CABG evaluated for bypass graft failure and progression of native coronary artery disease (CAD). Follow-up will be collected through national registry databases, electronic medical patient records and standardized telephonic assessment at 3 and 5 years follow-up.

Eligibility Criteria

Inclusion Criteria: * Prior coronary artery bypass grafting * One or more saphenous vein grafts * Recurrent angina symptoms Exclusion Criteria: * \<18 years of age * ≥ 90 years of age * Cardiogenic shock * Pregnancy * Failure to provide informed consent

Contact & Investigator

Central Contact

Paul Knaapen, Professor

✉ p.knaapen@amsterdamumc.nl

📞 +31 20 444 0123

Principal Investigator

Paul Knaapen, Professor

PRINCIPAL INVESTIGATOR

Amsterdam University Medical Centers, Department of Cardiology

Frequently Asked Questions

Who can join the NCT04772768 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Recurrent Angina After Coronary Artery Bypass Graft. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04772768 currently recruiting?

Yes, NCT04772768 is actively recruiting participants. Contact the research team at p.knaapen@amsterdamumc.nl for enrollment information.

Where is the NCT04772768 trial being conducted?

This trial is being conducted at Amsterdam, Netherlands.

Who is sponsoring the NCT04772768 clinical trial?

NCT04772768 is sponsored by Amsterdam UMC, location VUmc. The principal investigator is Paul Knaapen, Professor at Amsterdam University Medical Centers, Department of Cardiology. The trial plans to enroll 500 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology