NCT06972082 Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery
| NCT ID | NCT06972082 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Onassis Cardiac Surgery Centre |
| Condition | Acute Kidney Injury |
| Study Type | INTERVENTIONAL |
| Enrollment | 304 participants |
| Start Date | 2023-06-29 |
| Primary Completion | 2025-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 304 participants in total. It began in 2023-06-29 with a primary completion date of 2025-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main goal of this clinical trial is to learn if evaluation by ultrasound of venous congestion of liver and kidneys can guide treatment and prevent and treat acute kidney injury post cardiac surgery (CSA-AKI). Participants will: Be evaluated by liver and kidney veins ultrasound (treatment group) or a placebo post CSA-AKI. Fluid management for the treatment group will be based on a score that emerges from this evaluation (Venous Excess Ultrasound Score, VEXUS). Kidney function will be daily monitored and followed-up for 7 days and until discharge. Daily fluid balance and laboratory examination will be performed. Data will be recorded and collected and a statistical analysis will provide the results that will show or not a probable superiority of this evaluation comparing to the usual care.
Eligibility Criteria
Inclusion Criteria: * Patients in the Cardiac Surgery ICU who develop acute kidney injury according to KDIGO criteria, within 48 hours of ICU admission after cardiac surgery * Elective and non-elective cardiac surgery. Exclusion Criteria: * Patient refusal * Severe chronic renal failure (GFR\<15 mL/min/m2 or on hemodialysis). * Critical preoperative condition (severe cardiogenic shock, resuscitated cardiac arrest, support with mechanical circulatory assist devices). * Liver cirrhosis or inferior vena cava obstruction. * Pregnancy. * Morbid obesity (BMI\>40 kg/m2). * Delirium or other condition that prevents the performance of an ultrasound study.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06972082 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Kidney Injury. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06972082 currently recruiting?
Yes, NCT06972082 is actively recruiting participants. Contact the research team at stdimop@gmail.com for enrollment information.
Where is the NCT06972082 trial being conducted?
This trial is being conducted at Athens, Greece.
Who is sponsoring the NCT06972082 clinical trial?
NCT06972082 is sponsored by Onassis Cardiac Surgery Centre. The trial plans to enroll 304 participants.
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