| NCT ID | NCT02113644 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Maastricht University Medical Center |
| Condition | Cardiovascular Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 240 participants |
| Start Date | 2014-04 |
| Primary Completion | 2029-04 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
The aim of Prevent CardioKids is to evaluate to what extend disturbed vascular function markers are already present in children of different weight categories and whether these are age dependent. Also differences - and relationships - between vascular function measurements and plasma biomarkers between lean and overweight/obese children will be compared.
Eligibility Criteria
Inclusion Criteria: * Participation in the COACH program * Aged between 6 and 18 years (at time of inclusion) * Overweight or obesity according to IOTF criteria In order to be eligible to participate in the control group, a subject must meet all of the following criteria: * Aged between 6 and 18 years * Normal weight according to the IOTF criteria * Undergo surgery for elective reasons Exclusion Criteria: * Retarded children * Children suffering from: * Inflammatory diseases: auto-immune diseases, inflammatory bowel diseases, hepatitis, dermatitis, nephritis, pancreatitis, gastro-enteritis, vasculitis, salpingitis, arthritis, osteomyelitis, myositis, ear-nose-throat infections * Allergic diseases: asthma, eczema, hay fever, food allergies * Oncologic diseases * Cystic fibrosis * Type 1 diabetes mellitus * Congenital metabolic diseases * Malnourished children