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Recruiting NCT06517927

Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10

Trial Parameters

Condition Chemotherapy Effect
Sponsor Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study Type INTERVENTIONAL
Phase N/A
Enrollment 142
Sex ALL
Min Age 12 Years
Max Age 36 Years
Start Date 2024-05-03
Completion 2026-05-03
Interventions
Clinical and radiographic dental examination

Brief Summary

To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development. The aims of this study are : * Assess the caries risk in childhood cancer survivors compared with a control group. * Assess the dental development defects risk in childhood cancer survivors compared with a control group.

Eligibility Criteria

Inclusion Criteria: * age below 10 at cancer diagnosis (for the CCS group). * Chemotherapy must have been used to treat the patient (For the CCS group). * The patient is 12 years old or older at the time of the follow-up appointment of the present study Exclusion Criteria: * A patient who was diagnosed and treated after 10 years old. * Patient below 12 years old at time of study recruitment * Patients with syndrome or diseases that involve teeth impairment\* * Pregnant patient * Refusal or inaptitude to undergo dental and radiographic examination

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