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Recruiting NCT06908616
Prevalence of Ethnic Neutropenia and Duffy Null Phenotype in Neonates
Trial Parameters
Condition Neutropenia (Low White Blood Cell Count)
Sponsor Kaplan Medical Center
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,000
Sex ALL
Min Age 1 Minute
Max Age 1 Day
Start Date 2024-10-08
Completion 2026-12-31
Interventions
Cord blood
Brief Summary
This is a prospective observational study designed to assess the prevalence of the Duffy null phenotype (associated with ethnic neutropenia) in neonates born at Kaplan Medical Center. Blood samples will be collected from umbilical cords (non-invasively) to evaluate Duffy antigen expression. Data on ethnicity, perinatal factors, and routine blood counts at 9-12 months (when available) will also be collected to correlate phenotype with absolute neutrophil count (ANC).
Eligibility Criteria
Inclusion Criteria: * Neonates born at Kaplan Medical Center between 1.9.2024 and 31.12.2025 * Parental informed consent obtained * Umbilical cord blood available for routine testing Exclusion Criteria: * None