| NCT ID | NCT07368491 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Romina Belen Mattei |
| Condition | To Determine the Annual Prevalence of Airway Closure |
| Study Type | OBSERVATIONAL |
| Enrollment | 75 participants |
| Start Date | 2025-09-01 |
| Primary Completion | 2026-10 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 75 participants in total. It began in 2025-09-01 with a primary completion date of 2026-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary objective of this study is to describe the prevalence of airway closure during the total support phase of invasive mechanical ventilation in subjects admitted to an intensive care unit (ICU). The secondary objective is to analyze whether there are clinical-demographic and/or ventilatory characteristics associated with the presence of airway closure.
Eligibility Criteria
Inclusion Criteria: * Patients over 18 years of age * Requiring invasive mechanical ventilation within 48 to 72 hours after orotracheal intubation * Hemodynamically stable (mean arterial pressure greater than 60 mmHg and/or norepinephrine less than 0.5 mcg/kg/min) * Without respiratory muscle effort Exclusion Criteria: * Neumothorax * Bronchopleural fistula * Clinical evidence or suspicion of elevated intracranial pressure (greater than 18 mmHg)
Contact & Investigator
Romina B Mattei
PRINCIPAL INVESTIGATOR
CMPFA Churruca-Visca
Frequently Asked Questions
Who can join the NCT07368491 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying To Determine the Annual Prevalence of Airway Closure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07368491 currently recruiting?
Yes, NCT07368491 is actively recruiting participants. Contact the research team at rominabelenmattei@gmail.com for enrollment information.
Where is the NCT07368491 trial being conducted?
This trial is being conducted at Buenos Aires, Argentina.
Who is sponsoring the NCT07368491 clinical trial?
NCT07368491 is sponsored by Romina Belen Mattei. The principal investigator is Romina B Mattei at CMPFA Churruca-Visca. The trial plans to enroll 75 participants.