NCT06637436 PrEP Readiness Interventions for Sustained Motivation (PRISM)
| NCT ID | NCT06637436 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Florida International University |
| Condition | HIV |
| Study Type | INTERVENTIONAL |
| Enrollment | 400 participants |
| Start Date | 2025-01-28 |
| Primary Completion | 2027-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 400 participants in total. It began in 2025-01-28 with a primary completion date of 2027-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI) for optimizing entry or re-entry into the HIV prevention or care continua. A total of 400 participants will be randomized to CM (n = 200) or MI+CM (n = 200), all delivered via telehealth. Monthly follow-up assessments will be completed over 12 months to examine effectiveness MI+CM for the primary outcome - filling a pre-exposure prophylaxis (PrEP) or anti-retroviral therapy (ART) prescription (verified using a digital photo). Secondary outcomes will include: self-reported PrEP or ART clinical evaluation by a provider; self-reported meth and other substance use severity (ASSIST), and self-reported receptive and insertive condomless anal sex (CAS).
Eligibility Criteria
Inclusion Criteria: * 18 years or older * Assigned male a birth * Self-reported methamphetamine use in the past 3 months * HIV-negative or unknown serostatus at baseline * Has not filled a PrEP prescription in the past 6 months Exclusion Criteria: * Unwilling or unable to provide informed consent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06637436 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying HIV. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06637436 currently recruiting?
Yes, NCT06637436 is actively recruiting participants. Contact the research team at acarrico@fiu.edu for enrollment information.
Where is the NCT06637436 trial being conducted?
This trial is being conducted at Miami, United States.
Who is sponsoring the NCT06637436 clinical trial?
NCT06637436 is sponsored by Florida International University. The trial plans to enroll 400 participants.
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