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hiv

Total Trials
31
Recruiting Now
31
Trial Phases
Phase 2, Phase 1, Phase 4

ClinicalMetric tracks all active clinical trials for hiv sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.

  • Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
  • Phase 1–4 studies from early safety trials to post-marketing surveillance
  • NIH, pharmaceutical sponsor, and academic medical center studies worldwide
  • AI-powered plain-language summary available for every trial listing

Frequently Asked Questions — hiv Clinical Trials

How many clinical trials are currently recruiting for hiv?
ClinicalMetric currently tracks 31 actively recruiting clinical trials for hiv, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 31. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for hiv?
hiv research spans Phase 1 (3 trials), Phase 2 (4 trials), Phase 4 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a hiv clinical trial?
Eligibility criteria for hiv trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
3
Phase 2
4
Phase 4
3
Top Sponsors
Yale University 3 trials
Massachusetts General Hospital 3 trials
University of Alabama at Birmingham 2 trials
Boston University 2 trials
University of California, San Francisco 2 trials

Recruiting Clinical Trials

NCT07025109
Recruiting

Assessing Peer Support for Physical Activity in Women With HIV and Hypertension

Enrollment
50 pts
Location
United States
Sponsor
University of Alabama at Birmi...
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NCT04653610
Recruiting

Sequential Analysis Before and After Treatment Initiation to Unravel the Role of Naturally Occurring Extracellular Vesicles in HIV Infection

Enrollment
105 pts
Location
Belgium
Sponsor
University Hospital, Ghent
View Trial →
NCT06900829
Recruiting

#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.

Enrollment
5,200 pts
Location
Belgium, France, Ger...
Sponsor
Casper Rokx
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NCT04149782
Recruiting

Gathering Records to Evaluate Antiretroviral Treatment-South Africa

Enrollment
7,000,000 pts
Location
South Africa
Sponsor
Boston University
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NCT06845046
Recruiting

A Study to Improve Skeletal Muscle in Veterans With HIV

Enrollment
70 pts
Location
United States
Sponsor
VA Office of Research and Deve...
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NCT07231640
Recruiting

PrOTECT AL: PrEP Optimization Through Enhanced Continuum Tracking

Enrollment
56 pts
Location
United States
Sponsor
University of Alabama at Birmi...
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NCT06624839 Phase 2
Recruiting

Evaluating Gardasil HPV Vaccine Humoral and Cellular Immune Responses in People With and Without HIV

Enrollment
120 pts
Location
United States
Sponsor
University of Maryland, Baltim...
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NCT07112001
Recruiting

A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression

Enrollment
60 pts
Location
United States
Sponsor
University of Florida
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NCT06751030
Recruiting

Community, Home-based Education, Screening Services Strategy to Increase Cervical Cancer Control Access for HIV-Positive Women in Nigeria

Enrollment
1,500 pts
Location
Nigeria
Sponsor
Emory University
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NCT06935838 Phase 2
Recruiting

Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV

Enrollment
12 pts
Location
United States
Sponsor
University of Hawaii
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NCT06513819 Phase 1
Recruiting

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Enrollment
100 pts
Location
United States
Sponsor
Yale University
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NCT06931431
Recruiting

UNCPM 22322 - Adaption of the Transition of Care Model for Post-Discharge HIV-NCD Care in Lilongwe, Malawi - MLATHO

Enrollment
75 pts
Location
Malawi
Sponsor
University of North Carolina, ...
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NCT02761200
Recruiting

Post Analytic Treatment Interruption Study

Enrollment
100 pts
Location
Thailand
Sponsor
SEARCH Research Foundation
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NCT05608421
Recruiting

1MoreStep: An Intervention to Increase HIV Care Engagement and Reduce Intimate Partner Violence Among Black Women Living With HIV

Enrollment
100 pts
Location
United States
Sponsor
Johns Hopkins University
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NCT06971367
Recruiting

IBIS Megastudy of Interventions to Encourage HIV Retesting

Enrollment
40,000 pts
Location
Kenya, Uganda
Sponsor
University of California, San ...
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NCT06796686 Phase 1
Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

Enrollment
42 pts
Location
United States
Sponsor
National Institute of Allergy ...
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NCT04158882
Recruiting

Gathering Records to Evaluate Antiretroviral Treatment-Zambia (GREAT )

Enrollment
1,200,000 pts
Location
Zambia
Sponsor
Boston University
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NCT06389565
Recruiting

Change My Story Task Shifted Mental Health Intervention

Enrollment
80 pts
Location
Nigeria
Sponsor
Massachusetts General Hospital
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NCT05887557
Recruiting

Multidisciplinary Low-Barrier and Mobile HIV Care to Improve Retention and Viral Suppression: Stakeholder-Engaged Design and Evaluation

Enrollment
400 pts
Location
United States
Sponsor
University of California, San ...
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NCT06617091 Phase 1
Recruiting

A Trial of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine, Administered to Healthy Adults Living Without and With HIV.

Enrollment
120 pts
Location
South Africa, Zimbab...
Sponsor
International AIDS Vaccine Ini...
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NCT00029445
Recruiting

Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors

Enrollment
400 pts
Location
United States
Sponsor
National Institute of Allergy ...
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NCT05669534 Phase 4
Recruiting

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Enrollment
256 pts
Location
United States
Sponsor
University of Connecticut
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NCT06474364 Phase 4
Recruiting

HIV Prevention and Care Interventions for Youth in Uganda

Enrollment
600 pts
Location
Uganda
Sponsor
MU-JHU CARE
View Trial →
NCT07040592 Phase 2
Recruiting

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

Enrollment
30 pts
Location
United States
Sponsor
Yale University
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NCT06741319
Recruiting

Behavioral and Psychosocial Characteristics of Clients Accessing Services at IHRI

Enrollment
300,000 pts
Location
Thailand
Sponsor
Institute of HIV Research and ...
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NCT05923333
Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV

Enrollment
200 pts
Location
South Africa
Sponsor
University of Cape Town
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NCT04810858
Recruiting

Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

Enrollment
220 pts
Location
United States
Sponsor
Wake Forest University Health ...
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NCT05570812 Phase 2
Recruiting

Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV

Enrollment
120 pts
Location
United States
Sponsor
Massachusetts General Hospital
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NCT05910268
Recruiting

Peru Decentralized HIV Care

Enrollment
1,450 pts
Location
United States, Peru
Sponsor
Yale University
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NCT07199335 Phase 4
Recruiting

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

Enrollment
100 pts
Location
United States
Sponsor
Massachusetts General Hospital
View Trial →
NCT06046079
Recruiting

Predictors of Health Service Utilizations Among Key Population in Washington DC

Enrollment
100 pts
Location
United States
Sponsor
Us Helping Us, People Into Liv...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology