Preoperative Prehabilitation in Patients Planned for Liver Transplantation
Trial Parameters
Brief Summary
The objective of this study is to determine the feasibility and effectiveness of a home-based multimodal prehabilitation program in patients anticipated to be waitlisted for LT. Patients will participate in an eight week prehabilitation program consisting of physical exercise, nutritional support, smoking cessation and psychological counselling.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years, * Anticipated waitlisting for LT, * Speaks the Dutch language, * Understands the purpose of the study and has given written informed consent. Exclusion Criteria: * Experienced a major adverse cardiovascular event in the past six months, * Experienced a cerebrovascular incident in the past six months, * Medical history of an uncontrolled heart rhythm disorder, * Hepatic encephalopathy grade 3 or 4, * Acute liver failure, * Acute-on-chronic liver failure, * Hospitalization at start of the study. * Non-treated esophageal varices (i.e., no previous variceal eradication endoscopy or adequately dosed NSBB)