NCT07563998 Prehospital Point-of-Care Hs-Troponin I for Rule-Out of Acute Myocardial Infarction in Patients Without ST-Segment Elevation
| NCT ID | NCT07563998 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Central Denmark Region |
| Condition | Myocardial Infarction (MI) |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 2026-07-01 |
| Primary Completion | 2027-05-14 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 2026-07-01 with a primary completion date of 2027-05-14.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
People who call emergency medical services (EMS) with chest pain or other possible heart-related symptoms are often taken to hospital for further testing. However, only a small proportion of these patients are ultimately diagnosed with a serious heart condition such as a heart attack. This means that many patients undergo hospital transport and evaluation even though their risk is low. In hospitals, a blood test called high-sensitivity cardiac troponin is commonly used to help diagnose or rule out heart attacks. It is not yet well established whether this type of test can be used safely and effectively earlier, in the prehospital setting. This study will investigate whether it is feasible to measure high-sensitivity troponin in the ambulance and how well the test can identify patients at low risk of serious heart conditions. A small blood sample will be taken as part of routine care and analyzed using a portable device. The test result will not be used to guide treatment or decisions during the study. The study will assess how well the test predicts heart-related events within 30 days and how practical it is to perform the test in real-life emergency settings. The results may help guide future research on how to improve early assessment and decision-making for patients with suspected heart disease.
Eligibility Criteria
Inclusion Criteria: * Age 18 years or older * Assessed by one of the participating EMS units equipped for POCT sampling * Presentation with symptoms suggestive of acute coronary syndrome * Planned transport to hospital for further evaluation Exclusion Criteria: * ST-segment elevation on prehospital electrocardiogram * Clinical condition requiring immediate life-saving intervention precluding study procedures * Interhospital transport * Prior inclusion in the study within 30 days
Contact & Investigator
Martin F Gude, MD, PhD
PRINCIPAL INVESTIGATOR
Central Denmark Region
Frequently Asked Questions
Who can join the NCT07563998 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Myocardial Infarction (MI). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07563998 currently recruiting?
Yes, NCT07563998 is actively recruiting participants. Contact the research team at martgude@rm.dk for enrollment information.
Where is the NCT07563998 trial being conducted?
This trial is being conducted at Aarhus N, Denmark.
Who is sponsoring the NCT07563998 clinical trial?
NCT07563998 is sponsored by Central Denmark Region. The principal investigator is Martin F Gude, MD, PhD at Central Denmark Region. The trial plans to enroll 500 participants.