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Recruiting NCT04760977

Prehospital Management of Hypotensive Trauma in HEMS

Trial Parameters

Condition Hypotension and Shock
Sponsor Azienda Usl di Bologna
Study Type OBSERVATIONAL
Phase N/A
Enrollment 500
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2021-05-01
Completion 2025-05-01
Interventions
Drugs administrationResuscitative endovascular balloon occlusion of the aortaBlood transfusions

Brief Summary

Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality. Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes. Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies. With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome

Eligibility Criteria

Inclusion Criteria: * Age \> 18 years * Witnessed traumatic event managed by HEMS * Shock at first evaluation (Systolic blood pressure \< 90 mmHg) * Suspect or obvious ongoing haemorrage Exclusion Criteria: * Patients in cardiac arrest at HEMS arrival in which resuscitation is not started or interrupted by HEMS crew

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