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Recruiting Phase 4 NCT05804591

NCT05804591 Pregabalin in the Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy (LSG).

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Clinical Trial Summary
NCT ID NCT05804591
Status Recruiting
Phase Phase 4
Sponsor Medical University of Warsaw
Condition Obesity
Study Type INTERVENTIONAL
Enrollment 90 participants
Start Date 2023-04-24
Primary Completion 2025-04-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Pregabalin 150mgPlacebo

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 90 participants in total. It began in 2023-04-24 with a primary completion date of 2025-04-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this clinical trial is to assess preemptive oral pregabalin administration in the obese patients undergoing laparoscopic sleeve gastrectomy. The main aims of the study are to evaluate postoperative pain treatment and effect on the intraoperative hemodynamical stability. The participants will be divided into 2 groups: with or without preemptive pregabalin administration.

Eligibility Criteria

Inclusion Criteria: * Sleeve gastrectomy in patients with BMI \> 40 or \>35 with comorbidities * Written informed consent Exclusion Criteria: * Patient's refusal * Known allergies to study medication * Inability to comprehend or participate In pain scoring scale * Inability to use intravenous patient controlled analgesia * Changes of operation extent during procedure * Revisional operations * End stage organ failure

Contact & Investigator

Central Contact

Piotr Mieszczański, MD

✉ piotr.mieszczanski@gmail.com

📞 669643205

Principal Investigator

Piotr Mieszczański, MD

PRINCIPAL INVESTIGATOR

Medical University of Warsaw

Frequently Asked Questions

Who can join the NCT05804591 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT05804591 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT05804591 currently recruiting?

Yes, NCT05804591 is actively recruiting participants. Contact the research team at piotr.mieszczanski@gmail.com for enrollment information.

Where is the NCT05804591 trial being conducted?

This trial is being conducted at Warsaw, Poland.

Who is sponsoring the NCT05804591 clinical trial?

NCT05804591 is sponsored by Medical University of Warsaw. The principal investigator is Piotr Mieszczański, MD at Medical University of Warsaw. The trial plans to enroll 90 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology