NCT07259499 Predictors of Emergency Department Use in Frail Patients
| NCT ID | NCT07259499 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pisa |
| Condition | Alzheimer s Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 110 participants |
| Start Date | 2023-11-19 |
| Primary Completion | 2025-12-31 |
Trial Parameters
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Brief Summary
When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed. While cognitive impairment is a known clinical risk factor, biomarkers of most prevalent dementias have been scarcely investigated as possible ED use predictors. Within this context, this prospective study aims at exploring whether plasma phospho-tau181 and cerebrovascular burden can predict ED use at 6 months in elderly non-autonomous patients, irrespective of frailty.
Eligibility Criteria
Inclusion Criteria: * fluency in Italian language, * age higher than 64 years, * loss of autonomies of daily living as assessed by the Katz Activities of Daily Living or in the Lawton Instrumental Activities of Daily Living questionnaires, * having performed routinary blood exams in the 6 months prior to recruitment * having performed head neuroimaging feasable for cerebrovascular burden assessment, i.e., Magnetic Resonance Imaging (MRI) or computed tomography (CT), in the 6 months prior to recruitment. Exclusion Criteria: * withdrawal of the informed consent
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