NCT06054360 Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
| NCT ID | NCT06054360 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Universitaire, Amiens |
| Condition | Postoperative Atrial Fibrillation |
| Study Type | OBSERVATIONAL |
| Enrollment | 334 participants |
| Start Date | 2023-10-09 |
| Primary Completion | 2026-10-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 334 participants in total. It began in 2023-10-09 with a primary completion date of 2026-10-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The incidence of postoperative atrial fibrillation (POAF) after cardiac surgery is around 30%. POAF increases the risk of developing permanent atrial fibrillation and raises the risk of cardiac decompensation, stroke, acute myocardial infarction, and death. While the role of the left atrium (LAF) in the pathophysiology of POAF is now well-established, the part of the right atrium (RA) remains poorly understood. Recent studies suggest a correlation between RA function and POAF. RA function can be assessed by transthoracic echocardiography (TTE) with dedicated software for measuring the RA strain (RAS). RA function is thus divided into three phases: reservoir (RASr), conduit, and contraction. Numerous studies have demonstrated that a significant alteration in RAS predicts POAF in various clinical contexts. Therefore, it is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery. It is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery.
Eligibility Criteria
Inclusion Criteria: * Adult patient (\>18 years old) * The patient was hospitalized at the Amiens University Hospital for scheduled aortocoronary bypass grafting under cardiopulmonary bypass. * Echocardiographic image quality enabling the measurement of RAS parameters * Patient affiliation to a social security scheme * Patient/proxy information and collection of their non-opposition. Exclusion Criteria: * Patients participating in an interventional study may modify the incidence of POAF. * History of atrial fibrillation or flutter. * Valvular and ascending aorta cardiac surgery * Urgent cardiac surgery. * Presence of tricuspid insufficiency greater than grade 2. * Left ventricular ejection fraction lower than 50%. * Patient receiving circulatory mechanical assistance before surgery. * Dependency on ventricular and atrial pacing by an internal or external cardiac pacemaker during the echocardiographic examination.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06054360 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Postoperative Atrial Fibrillation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06054360 currently recruiting?
Yes, NCT06054360 is actively recruiting participants. Contact the research team at daumin.camille@chu-amiens.fr for enrollment information.
Where is the NCT06054360 trial being conducted?
This trial is being conducted at Amiens, France.
Who is sponsoring the NCT06054360 clinical trial?
NCT06054360 is sponsored by Centre Hospitalier Universitaire, Amiens. The trial plans to enroll 334 participants.
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