NCT06532994 Predictive Algorithms for Critical Rehabilitation Outcomes
| NCT ID | NCT06532994 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Wuhan University |
| Condition | Intensive Care |
| Study Type | OBSERVATIONAL |
| Enrollment | 250 participants |
| Start Date | 2024-08-01 |
| Primary Completion | 2026-10-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 250 participants in total. It began in 2024-08-01 with a primary completion date of 2026-10-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
An increasing amount of evidence from evidence-based medicine indicates that early rehabilitation intervention for patients receiving mechanical ventilation is safe and feasible, and can promote functional recovery and reduce hospital stay. However, the conscious state, respiratory function, and daily living activities of these patients after being discharged from the ICU vary greatly, and some patients do not show obvious benefits. How to identify which patients may have benefit from early rehabilitation is a key issue that needs to be addressed in critical care rehabilitation. This study aims to investigate the clinical data related to the disease of the ICU survivors who received mechanical ventilation as the research object, by collecting their clinical data when receiving early rehabilitation intervention, and constructing a clinical prediction model for the efficacy of early rehabilitation intervention in the ICU through the selection of optimal regression equation or machine learning algorithm. The application of this model can effectively determine whether ICU inpatients need early rehabilitation intervention, thereby reducing complication rates and improving their quality of life.
Eligibility Criteria
Inclusion Criteria: 1. Age older than 18 years; 2. Received mechanical ventilation, including endotracheal intubation and tracheostomy, during ICU admission; 3. Met the rehabilitation intervention indications outlined in the "Chinese Expert Consensus on Neurocritical Rehabilitation" during ICU admission and underwent corresponding early rehabilitation interventions, including but not limited to arousal therapy for consciousness disorders, early active/passive mobilization, comprehensive pulmonary rehabilitation, etc.; 4. No mortality events occurred during ICU admission; 5. Informed consent form signed by family members or the patient. Exclusion Criteria: 1. Pediatric patients under 18 years of age; 2. Hospitalized patients in the ICU who did not receive mechanical ventilation; 3. Patients in the ICU who did not undergo early rehabilitation interventions; 4. mortality events occurred during ICU admission; 5. Patients transferred out of the ICU due to treatment abandonment by family members; 6. Family refusal to sign the informed consent form or patient refusal to sign the informed consent form when conscious and competent.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06532994 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Intensive Care. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06532994 currently recruiting?
Yes, NCT06532994 is actively recruiting participants. Contact the research team at shuqingj@whu.edu.cn for enrollment information.
Where is the NCT06532994 trial being conducted?
This trial is being conducted at Wuhan, China.
Who is sponsoring the NCT06532994 clinical trial?
NCT06532994 is sponsored by Wuhan University. The trial plans to enroll 250 participants.