NCT05812248 Prediction of Vascular Events After Major Non-Cardiac Surgery : an Observational Prospective Cohort Study
| NCT ID | NCT05812248 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Nanfang Hospital, Southern Medical University |
| Condition | Noncardiac Surgery |
| Study Type | OBSERVATIONAL |
| Enrollment | 20,000 participants |
| Start Date | 2022-07-01 |
| Primary Completion | 2027-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 20,000 participants in total. It began in 2022-07-01 with a primary completion date of 2027-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This observational study includes patients at medium-to-high cardiovascular risks undergoing major noncardiac surgery, measures their baseline demographic and clinical characteristics, preoperative cardiac biomarkers and intraoperative surgery/anesthesia related data, and screens them for the occurrence of myocardial injury and major adverse cardiac events after surgery. The primary aim is to develop and validate a pre- and an immediate postoperative prediction model for occurrence of major adverse cardiac events.
Eligibility Criteria
Inclusion Criteria: * Age ≥ 45 years; * Undergoing major noncardiac surgery (expected procedure duration ≥2 h, expected length of postoperative stay ≥2 d); * History of at least one cardiovascular disease (i.e., coronary artery disease, stroke, congestive heart failure, or peripheral arterial disease) or with at least two cardiovascular risk factors (i.e., hypertension, diabetes, chronic kidney disease, smoking in the past ≥2 years, ≥65 years of age, hypercholesterolemia, history of TIA, high-risk surgery (intrathoracic, intraperitoneal, or major vascular)). Exclusion Criteria: * History of acute cardiovascular events within 30 days prior to surgery; * American Society of Anesthesiologists (ASA) physical status of 5 or greater; * Previously enrolled in this study; * Unable to understand or to sign informed consent.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05812248 clinical trial?
This trial is open to participants of all sexes, aged 45 Years or older, studying Noncardiac Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05812248 currently recruiting?
Yes, NCT05812248 is actively recruiting participants. Contact the research team at zhaobch@mail2.sysu.edu.cn for enrollment information.
Where is the NCT05812248 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT05812248 clinical trial?
NCT05812248 is sponsored by Nanfang Hospital, Southern Medical University. The trial plans to enroll 20,000 participants.