NCT06346158 Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia
| NCT ID | NCT06346158 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ciusss de L'Est de l'Île de Montréal |
| Condition | Anesthesia |
| Study Type | OBSERVATIONAL |
| Enrollment | 110 participants |
| Start Date | 2025-04-07 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 110 participants in total. It began in 2025-04-07 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to explore the variability of the concentration at the effect site (Ce) of propofol to reach deep anesthesia (DA) during induction of general anesthesia in adults. The investigators hypothesized that there is a great variability in this Ce that could be precisely explained by * Electroencephalographic (EEG) features available prior to induction of anesthesia * Cognitive performance * Patients characteristics Participants will undergo preoperative cognitive testing and awake EEG. Then, induction of general anesthesia will be performed using continuous infusion of propofol. The Ce at which Deep anesthesia is observed will be recorded.
Eligibility Criteria
Inclusion Criteria: * Scheduled for any kind of surgery under general anesthesia. * Adults Exclusion Criteria: * Inability to communicate in French or English, * Known allergy or intolerance or other medical condition that precludes the use of prescribed general anesthesia protocol for this study, * Patients requiring rapid sequence induction, * Anticipated or known difficult intubation patient, * Anticipated or known difficult ventilation patient, * Body mass index ≥ 35 kg.m-2.
Contact & Investigator
Louis Morisson, MD, MSc
PRINCIPAL INVESTIGATOR
CIUSSS de l'Est de l'Ile de Montréal
Frequently Asked Questions
Who can join the NCT06346158 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Anesthesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06346158 currently recruiting?
Yes, NCT06346158 is actively recruiting participants. Contact the research team at louis.morisson@umontreal.ca for enrollment information.
Where is the NCT06346158 trial being conducted?
This trial is being conducted at Montreal, Canada.
Who is sponsoring the NCT06346158 clinical trial?
NCT06346158 is sponsored by Ciusss de L'Est de l'Île de Montréal. The principal investigator is Louis Morisson, MD, MSc at CIUSSS de l'Est de l'Ile de Montréal. The trial plans to enroll 110 participants.