NCT06810349 Predicting Tumor Origin Based on Deep Learning of Lymph Node Puncture Cytology
| NCT ID | NCT06810349 |
| Status | Recruiting |
| Phase | — |
| Sponsor | West China Hospital |
| Condition | Lymph Nodes With Tumor Metastasis |
| Study Type | OBSERVATIONAL |
| Enrollment | 10,000 participants |
| Start Date | 2024-11-11 |
| Primary Completion | 2025-12 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
In this study, the investigators aimed to construct a deep learning diagnostic model that uses cytological images to predict primary unknown tumor origins in patients with tumors combined with lymph node metastases. After the model is constructed, the model will be validated by a large-scale test set to test the model performance. The investigators also propose to compare the performance of the constructed model in diagnosing cytology smears compared to human pathologists.
Eligibility Criteria
Inclusion Criteria: * From West China Hospital of Sichuan University (October 1, 2008-August 31, 2024) with corresponding clinical data, including age, sex, specimen puncture site, pathologic diagnosis, pathologic type, whether immunocytochemistry was added, clinical diagnosis, lesion site, co-morbidities, history of malignancy, treatment modality, occurrence of postoperative complications, total number of days of hospitalization postoperatively, and survival time; * From the Department of Pathology of the First Affiliated Hospital of Zhengzhou University, the Sichuan Provincial Cancer Hospital, and the Cancer Hospital of the Chinese Academy of Medical Sciences (January 1, 2020-August 31, 2024) with corresponding clinical data, including age, sex, specimen puncture site, pathologic diagnosis, pathologic type, whether immunocytochemistry was added, clinical diagnosis, lesion site, co-morbidities, history of malignancy, treatment modality, occurrence of postoperative complications, total