NCT04535843 Precision Diagnosis and Prospective Cohort Study for Myasthenia Gravis: Multicenter Analysis in China
| NCT ID | NCT04535843 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Huashan Hospital |
| Condition | Myasthenia Gravis |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 2024-02-01 |
| Primary Completion | 2028-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 2024-02-01 with a primary completion date of 2028-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The present study is a prospective cohort study aiming to improve the clinical capacity in the diagnosis and natural history of Chinese patients with myasthenia gravis (MG). 300 MG patients are planned to recruit, document and prospectively follow up. Management of screening test and cohort manifestation are studied.
Eligibility Criteria
Inclusion Criteria: * fluctuating muscle weakness and fatigability, along with one of the below: * more than 10% amplitude decrement in low frequency repetitive nerve stimulation,less than 10% amplitude increment in high frequency repetitive nerve stimulation; * anti-AChR or MuSK antibody positivity; * positive to the neostigmine test; * understanding and assigning the informed consent form, and having a good compliance with the follow up. Exclusion Criteria: * excluding the possible diagnosis of Lambert-Eaton syndrome, congenital myasthenia syndrome,botulism injection, chronic progressive extraocular ophthalmoplegia, etc; * poor compliance to the follow up.
Contact & Investigator
Chongbo Zhao, MD
STUDY CHAIR
Huashan Hospital, Shanghai,China
Frequently Asked Questions
Who can join the NCT04535843 clinical trial?
This trial is open to participants of all sexes, aged 0 Years or older, up to 90 Years, studying Myasthenia Gravis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04535843 currently recruiting?
Yes, NCT04535843 is actively recruiting participants. Contact the research team at zhao_chongbo@fudan.edu.cn for enrollment information.
Where is the NCT04535843 trial being conducted?
This trial is being conducted at Shanghai, China, Shanghai, China, Shanghai, China, Shanghai, China.
Who is sponsoring the NCT04535843 clinical trial?
NCT04535843 is sponsored by Huashan Hospital. The principal investigator is Chongbo Zhao, MD at Huashan Hospital, Shanghai,China. The trial plans to enroll 500 participants.