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Recruiting Phase 2 NCT06119789

NCT06119789 Precision Cancer Therapy in Rare Cancers

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Clinical Trial Summary
NCT ID NCT06119789
Status Recruiting
Phase Phase 2
Sponsor Oslo University Hospital
Condition Rare Malignant Neoplasm
Study Type INTERVENTIONAL
Enrollment 96 participants
Start Date 2025-03-20
Primary Completion 2033-11-30

Eligibility & Interventions

Sex All sexes
Min Age 16 Years
Max Age 99 Years
Study Type INTERVENTIONAL
Interventions
ImatinibTrametinibDabrafenib

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 96 participants in total. It began in 2025-03-20 with a primary completion date of 2033-11-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Some rare cancers are hard-to-treat and patients have a poor prognosis. It is known that some of these patients have targetable molecular alterations, and some benefit from targeted drugs. However in many cases these drugs are not approved for the rare cancers. In this study the aim is to do advanced molecular diagnostics to identify possible targets for therapy, and to treat accordingly.

Eligibility Criteria

Inclusion Criteria: * ECOG 0-2, * identified biomarker, * reasonable biochemistry Exclusion Criteria: * ECOG 3-5 * serious other diseases

Contact & Investigator

Central Contact

Åslaug Helland, MD PhD

✉ ahelland@medisin.uio.no

📞 +4795940863

Principal Investigator

Sigbjørn Smeland, MD PhD

STUDY CHAIR

Oslo University Hospital

Frequently Asked Questions

Who can join the NCT06119789 clinical trial?

This trial is open to participants of all sexes, aged 16 Years or older, up to 99 Years, studying Rare Malignant Neoplasm. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06119789 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT06119789 currently recruiting?

Yes, NCT06119789 is actively recruiting participants. Contact the research team at ahelland@medisin.uio.no for enrollment information.

Where is the NCT06119789 trial being conducted?

This trial is being conducted at Oslo, Norway.

Who is sponsoring the NCT06119789 clinical trial?

NCT06119789 is sponsored by Oslo University Hospital. The principal investigator is Sigbjørn Smeland, MD PhD at Oslo University Hospital. The trial plans to enroll 96 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology