NCT06290336 Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement
| NCT ID | NCT06290336 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Linkoeping University |
| Condition | Knee Osteoarthritis |
| Study Type | INTERVENTIONAL |
| Enrollment | 110 participants |
| Start Date | 2024-02-26 |
| Primary Completion | 2027-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 110 participants in total. It began in 2024-02-26 with a primary completion date of 2027-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this multi-center randomized controlled trial is to investigate the effect of pre-operative exercise therapy and education for patients awaiting knee replacement surgery on subjective knee function, patient satisfaction and enablement compared to standard care. The main questions it aims to answer are: * Does pre-operative exercise therapy and education lead to better subjective knee function compared to standard care one year after surgery? * Does pre-operative exercise therapy and education lead to a higher level of patient satisfaction compared to standard care one year after surgery? * Does pre-operative exercise therapy and education lead to better patient enablement compared to standard care six weeks after surgery? * Does pre-operative exercise therapy and education lead to better objective knee function compared to standard care six weeks after surgery? Participants will be randomized stratified by age (≤ 67 years, \> 67 years) to either pre-operative supervised individualized exercise therapy combined with education two sessions/week (intervention group) or to standard care (control group). The intervention will be continuously ongoing for at least eight weeks from the point of decision for surgery until as close to the surgery as possible.
Eligibility Criteria
Inclusion Criteria: * Waiting list for primary unilateral knee replacement surgery * Osteoarthritis of the knee being the primary reason for surgery * Reside within 60 minutes of travel to the site of the intervention Exclusion Criteria: * Previous knee replacement surgery in the other knee * Other reason than osteoarthritis of the knee as the primary reason for surgery * Impaired cognitive function * Not being independent speaking and reading in swedish language * Chronic illness or disability etc hindering full participation in the intervention
Contact & Investigator
Marcus Ljung, PhD-student
STUDY DIRECTOR
Linkoeping University
Frequently Asked Questions
Who can join the NCT06290336 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 85 Years, studying Knee Osteoarthritis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06290336 currently recruiting?
Yes, NCT06290336 is actively recruiting participants. Contact the research team at marcus.ljung@regionostergotland.se for enrollment information.
Where is the NCT06290336 trial being conducted?
This trial is being conducted at Linköping, Sweden.
Who is sponsoring the NCT06290336 clinical trial?
NCT06290336 is sponsored by Linkoeping University. The principal investigator is Marcus Ljung, PhD-student at Linkoeping University. The trial plans to enroll 110 participants.