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Recruiting Phase 4 NCT05709626

NCT05709626 PRasugrEl Monotherapy Following prImary percUtaneous Coronary Intervention for ST-elevation Myocardial Infarction

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Clinical Trial Summary
NCT ID NCT05709626
Status Recruiting
Phase Phase 4
Sponsor Kindai University
Condition ST-segment Elevation Myocardial Infarction (STEMI)
Study Type INTERVENTIONAL
Enrollment 2,258 participants
Start Date 2023-02-28
Primary Completion 2025-01-04

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
No aspirin (Prasugurel monotherapy)12-month DAPT

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 2,258 participants in total. It began in 2023-02-28 with a primary completion date of 2025-01-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this study is to evaluate the safety of prasugrel monotherapy without aspirin versus 12-month dual antiplatelet therapy (DAPT) in patients with STEMI using platinum-chrome everolimus-eluting stent (PtCr-EES: SYNERGYTM).

Eligibility Criteria

Inclusion Criteria: * Patients scheduled for primary PCI with everolimus-eluting stent (PtCr-EES, SYNERGYTM) * STEMI patients * Patients who can continue dual antiplatelet therapy with aspirin and a P2Y12 inhibitor for 12 months Exclusion Criteria: * Patients taking anticoagulants * Patients under 18 years old * Patients with less than 1 year prognosis * Patients participating in other intervention studies

Contact & Investigator

Central Contact

Kuniaki Takahashi, MD, PhD

✉ kuniaki.t.0125@gmail.com

📞 +81-72-366-0221

Principal Investigator

Gaku Nakazawa, MD, PhD

PRINCIPAL INVESTIGATOR

Kindai University Faculty of Medicine

Frequently Asked Questions

Who can join the NCT05709626 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying ST-segment Elevation Myocardial Infarction (STEMI). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT05709626 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT05709626 currently recruiting?

Yes, NCT05709626 is actively recruiting participants. Contact the research team at kuniaki.t.0125@gmail.com for enrollment information.

Where is the NCT05709626 trial being conducted?

This trial is being conducted at Sayama, Japan.

Who is sponsoring the NCT05709626 clinical trial?

NCT05709626 is sponsored by Kindai University. The principal investigator is Gaku Nakazawa, MD, PhD at Kindai University Faculty of Medicine. The trial plans to enroll 2,258 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology