NCT07639203 PotenziaMente: A Digital Executive Function Training Intervention for Healthy Aging in the Elderly Population
| NCT ID | NCT07639203 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Università degli Studi di Trento |
| Condition | Aging and Cognitive Health |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2024-09-17 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2024-09-17 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study, entitled "PotenziaMente: Cognitive Training in Aging," is a clinical trial designed to evaluate the effectiveness of an individualized tablet-based cognitive training program targeting executive functions (e.g., planning, cognitive flexibility, and problem solving) in healthy older adults. Executive functions are higher-order cognitive processes that support adaptive functioning in daily life and influence other cognitive domains, such as memory. The primary aim of the study is to enhance cognitive performance, specifically executive functioning, in neurologically healthy adults aged 65 to 75 years. A secondary aim is to compare the effects of two different delivery modalities of the same cognitive training program: home-based self-administration via tablet versus supervised tablet-based training in the presence of a trained researcher. Participants will undergo cognitive assessments at baseline (pre-training), immediately after the intervention (post-training), and at a 3-month follow-up. This is a randomized parallel-group interventional clinical trial without masking. Participants are randomly assigned to one of two groups: a home-based cognitive training condition, in which they perform an individualized tablet-based cognitive training program targeting executive functions independently at home via a tablet application without direct supervision, or a supervised cognitive training condition, in which they perform the same individualized tablet-based cognitive training under the supervision of a trained researcher in a controlled environment. The intervention consists of two sessions per week, 1 hour per session, for 4 consecutive weeks, delivered via tablet-based exercises. The study uses a parallel assignment model with a prospective design and a primary purpose of treatment (cognitive enhancement and prevention of cognitive decline). The primary outcome is the change in executive functioning from baseline to post-intervention, assessed using standardized neuropsychological tests. Secondary outcomes include between-group differences (home-based vs. supervised) in executive functioning, changes in global cognitive functioning from baseline to post-intervention, and maintenance of cognitive effects at the 3-month follow-up.
Eligibility Criteria
Inclusion Criteria: Cognitively healthy adults aged 65 to 75 years. Montreal Cognitive Assessment (MoCA) equivalent score ≥ 1, according to Italian normative values. Exclusion Criteria: History of current or previous neurological or neuropsychiatric disorders.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07639203 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, up to 75 Years, studying Aging and Cognitive Health. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07639203 currently recruiting?
Yes, NCT07639203 is actively recruiting participants. Contact the research team at beatrice.feder@unitn.it for enrollment information.
Where is the NCT07639203 trial being conducted?
This trial is being conducted at Rovereto, Italy.
Who is sponsoring the NCT07639203 clinical trial?
NCT07639203 is sponsored by Università degli Studi di Trento. The trial plans to enroll 60 participants.