NCT06065306 Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department
| NCT ID | NCT06065306 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese University of Hong Kong |
| Condition | Aortic Dissection |
| Study Type | OBSERVATIONAL |
| Enrollment | 47 participants |
| Start Date | 2023-06-18 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 47 participants in total. It began in 2023-06-18 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to determine the utility of desmosine, D-dimer and aggrecan as early diagnostic biomarkers in aortic dissection. The main questions it aims to answer are: * To investigate the plasma levels of selected biomarkers in ED patients with confirmed aortic dissection * To study the diagnostic performance of plasma levels of selected biomarkers for aortic dissection * To study the association between plasma levels of selected biomarkers and clinical outcomes
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Presentation to the ED with first 24 hours of symptoms suggesting AD, including chest pain, upper back pain, syncope of unknown cause, symptoms of any acute perfusion deficit * Confirmed AD * the diagnosis of AD adjudicated by an independent expert panel at hospital discharge or death, whichever comes first * The expert panel will consist of (1) a specialist in Emergency Medicine and (2) a specialist in Cardiology and (3) a specialist in Cardiothoracic Surgery. Exclusion Criteria: * Age \<18 years old * Pregnancy * Surgery or stenting performed before recruitment
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06065306 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Aortic Dissection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06065306 currently recruiting?
Yes, NCT06065306 is actively recruiting participants. Contact the research team at cagraham@cuhk.edu.hk for enrollment information.
Where is the NCT06065306 trial being conducted?
This trial is being conducted at Shatin, Hong Kong.
Who is sponsoring the NCT06065306 clinical trial?
NCT06065306 is sponsored by Chinese University of Hong Kong. The trial plans to enroll 47 participants.