NCT07163858 Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
| NCT ID | NCT07163858 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Infirmerie Protestante de Lyon |
| Condition | Coronary Artery Disease With Need for Bypass Surgery |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-10-06 |
| Primary Completion | 2027-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-10-06 with a primary completion date of 2027-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.
Eligibility Criteria
Inclusion Criteria: * Adult patient * patient requiring isolated coronary bypass surgery * Elective procedure or medical emergency * First cardiac surgery * Patient with an EF ≥30% * Mandatory affiliation to a social security system * Signed informed consent form * Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure Exclusion Criteria: * Contraindication to an inotropic substance (only NA will be used) * Contraindication to passive leg raising * Patient in a life-threatening emergency * History of cardiac surgery * Bilateral iliac or common femoral artery occlusion * EF \< 30% * Pregnancy and breastfeeding * Renal failure (GFR \< 40 ml/min/1.73 m²) * Patient with bilateral thigh amputation * Class III obesity BMI \> 40 kg/m²
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07163858 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Coronary Artery Disease With Need for Bypass Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07163858 currently recruiting?
Yes, NCT07163858 is actively recruiting participants. Contact the research team at recherche-clinique@infirmerie-protestante.com for enrollment information.
Where is the NCT07163858 trial being conducted?
This trial is being conducted at Caluire-et-Cuire, France.
Who is sponsoring the NCT07163858 clinical trial?
NCT07163858 is sponsored by Infirmerie Protestante de Lyon. The trial plans to enroll 50 participants.