Post Pandemic Pneumococcal Carriage Among Children and Adults
Trial Parameters
Brief Summary
The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city. These data will allow PI to assess the post-pandemic population structure, investigate the phylogenetic relationship between isolates from children and adults, and compare pneumococcal populations across diverse geographic areas.
Eligibility Criteria
Inclusion Criteria: * Children, ages 7 to 59 months (less than 5 years) * Adults, ages 50 and older * Ability to provide informed consent (from parents for children participants) * ability to read and speak in English * Agree to comply with study procedures (complete online data questionnaire and provide a nasopharyngeal collection). Exclusion Criteria: * Have been on an antibiotic in the last 2 weeks * Have a respiratory infection that would make an nasopharyngeal collection improbable * Have underlying developmental or chronic conditions impacting immune or respiratory function (e.g., immunocompromised, cystic fibrosis, cerebral palsy, paralysis) * Adults unable to consent, individuals who are not yet adults, and prisoners will be excluded from this study.