NCT07174921 Post-hysterectomy Vaginal Cuff Prolapse Repair
| NCT ID | NCT07174921 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kanuni Sultan Suleyman Training and Research Hospital |
| Condition | Vaginal Cuff Complications |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-09-30 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-09-30 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is a randomized controlled trial comparing two minimally invasive surgeries-laparoscopic lateral suspension and laparoscopic sacrocolporopexy-for women who develop vaginal cuff prolapse after hysterectomy. Vaginal cuff prolapse occurs when the top of the vagina loses support after the uterus is removed, which can cause discomfort, bulging, or urinary and bowel problems. The goal of this study is to determine which surgical approach is safer, more effective, and improves quality of life for patients. Women enrolled in the trial will be randomly assigned to one of the two surgeries, and outcomes such as prolapse recurrence, complications, recovery time, and patient satisfaction will be carefully monitored. By comparing these two techniques, this study aims to provide clear guidance for surgeons and patients to make informed decisions about the best surgical treatment for post-hysterectomy vaginal cuff prolapse.
Eligibility Criteria
Inclusion Criteria: Women aged ≥18 years. History of hysterectomy (any approach: abdominal, vaginal, or laparoscopic). Symptomatic vaginal cuff prolapse (POP-Q stage ≥ II). Able to provide written informed consent. Willing and able to comply with study procedures and follow-up visits. Exclusion Criteria: Prior sacrocolpopexy or lateral suspension surgery. Active pelvic infection or untreated malignancy. Severe cardiopulmonary or systemic disease that contraindicates laparoscopic surgery. Known allergy to mesh materials used in the procedures. Inability to complete patient-reported questionnaires due to cognitive or language barriers. Concurrent pelvic organ prolapse requiring additional surgical repair beyond vaginal cuff suspension.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07174921 clinical trial?
This trial is open to female participants only, aged 18 Years or older, studying Vaginal Cuff Complications. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07174921 currently recruiting?
Yes, NCT07174921 is actively recruiting participants. Contact the research team at dr.ozankrdnz@gmail.com for enrollment information.
Where is the NCT07174921 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07174921 clinical trial?
NCT07174921 is sponsored by Kanuni Sultan Suleyman Training and Research Hospital. The trial plans to enroll 50 participants.