NCT06757218 Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
| NCT ID | NCT06757218 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kafrelsheikh University |
| Condition | Alveolar Socket Preservation |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-06-01 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2025-06-01 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used. Autogenous dentin, taken from the patient, supports healing and bone regrowth. Platelet-rich fibrin (PRF), made from the patient's blood, enhances healing and bone density by releasing growth factors. A new technique combining L-PRF with albumin creates a stable healing membrane that provides a steady release of growth factors. Overall, these methods improve recovery after tooth extractions and prepare sites for future dental work.
Eligibility Criteria
Inclusion Criteria: * Medically free patients. * Adult patients above 18 Years to 60 Years. * Non-restorable tooth indicated for extraction. * Posterior mandibular teeth. * Inactive infection related to the tooth. * Cooperative patients. Exclusion Criteria: * Presence of any systemic disease that could influence the outcome of the therapy. * Presence of any risk factor (smoker, pregnant and lactating patients). * Patients with bone diseases. * Patients with poor oral hygiene.
Contact & Investigator
Enas Ahmed Elgendy, PhD
STUDY DIRECTOR
Kaferelsheikh University
Frequently Asked Questions
Who can join the NCT06757218 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Alveolar Socket Preservation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06757218 currently recruiting?
Yes, NCT06757218 is actively recruiting participants. Contact the research team at muath_01pg@den.kfs.edu.eg for enrollment information.
Where is the NCT06757218 trial being conducted?
This trial is being conducted at Kafr ash Shaykh, Egypt.
Who is sponsoring the NCT06757218 clinical trial?
NCT06757218 is sponsored by Kafrelsheikh University. The principal investigator is Enas Ahmed Elgendy, PhD at Kaferelsheikh University. The trial plans to enroll 60 participants.