NCT07774845 Platelets and Plasma Lipids Relationship as a Biomarker and Potential Therapeutic Target of Thrombogenesis
| NCT ID | NCT07774845 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Sao Paulo |
| Condition | Cardio Vascular Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 45 participants |
| Start Date | 2026-03-05 |
| Primary Completion | 2026-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 45 participants in total. It began in 2026-03-05 with a primary completion date of 2026-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of this clinical trial is to compare the effect of two different lipid emulsion formulations versus no emulsion on platelet aggregation in individuals without a history of ischemic disease. The hypothesis of this study is: Platelet aggregation is inversely associated with higher plasma lipid concentrations. The researchers will compare platelet aggregation in the presence and absence of lipid nanoemulsions in vitro through three pathways using the agonists collagen, adenosine diphosphate, and arachidonic acid. The tests will be performed using light-transmission aggregometry. Various participant parameters, such as lipid profile, will be evaluated to analyze possible correlations with the observed results. Participants must: Meet the study's inclusion criteria; Sign the informed consent form; Report to the blood draw laboratory at InCor's AB on the scheduled date and time after fasting for at least 8 hours.
Eligibility Criteria
Inclusion Criteria: * Men and women aged ≥ 40 years. * Willingness to sign the informed consent form. * Absence of known atherosclerotic disease Exclusion Criteria: * Use of antiplatelet agents. * Use of anticoagulants. * Use of lipid-lowering agents. * Use of oral hypoglycemic agents or insulin. * Known atherosclerotic disease. * Refusal to sign the informed consent form
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07774845 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, studying Cardio Vascular Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07774845 currently recruiting?
Yes, NCT07774845 is actively recruiting participants. Contact the research team at jose.nicolau@fm.hc.usp.br for enrollment information.
Where is the NCT07774845 trial being conducted?
This trial is being conducted at São Paulo, Brazil.
Who is sponsoring the NCT07774845 clinical trial?
NCT07774845 is sponsored by University of Sao Paulo. The trial plans to enroll 45 participants.