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Recruiting NCT05705778

Plasma Biomarker in Amblyopia Patients

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Trial Parameters

Condition Amblyopia
Sponsor Zhongshan Ophthalmic Center, Sun Yat-sen University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 600
Sex ALL
Min Age 3 Years
Max Age 12 Years
Start Date 2022-11-01
Completion 2025-10-31
Interventions
standard amblyopia treatment

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Brief Summary

This prospective study aims to observe the predictive effect of peripheral blood plasma biomarker on the outcome of treatment in children with different types of amblyopia. We also investigated the mechanism of neuromodulation in the visual development of amblyopic children.

Eligibility Criteria

Inclusion Criteria: * Diagnosed with amblyopia * 3-12 years of age * Able to tolerate amblyopia treatment * Agree to be involved in this study and agree to have a follow up visit every 3 months. Exclusion Criteria: * Have previous treatment history before * Have pathological ocular anomalies known to cause reduced visual acuity * Have previous psychiatric, visual or neurological disorders * Have eccentric fixation and/or abnormal retinal correspondence * Have attention disorder and learning disability that cannot comprehend psychophysical test instructions given and/or consent for themselves

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