NCT07182240 Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas
| NCT ID | NCT07182240 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Roswell Park Cancer Institute |
| Condition | Basal Cell Carcinoma |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-12-22 |
| Primary Completion | 2027-06-22 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2025-12-22 with a primary completion date of 2027-06-22.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
To assess the feasibility and provide information on the utility of noninvasive line field confocal optical coherence tomography (LC-OCT) for the presurgical assessment of Mohs micrographic surgery sites in patients undergoing removal of cutaneous basal cell carcinomas (BCC).
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Participant must understand the investigational nature of this study and provide written consent prior to receiving any study-related procedure. * Participant must be clinically eligible for Mohs surgery as determined by their referring dermatologist and the Mohs surgeon. * The participant must have a BCC with superficial histology or a BCC with multiple histological features that also include superficial histology, which is appropriate for Mohs surgery. Exclusion Criteria: * Known or reported allergy to mineral oil, the optical agent used during imaging. * Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements. * . Any condition which in the investigator's opinion deems the subject an unsuitable candidate to undergo imaging procedure. * Unwilling or unable to follow protocol requirements
Contact & Investigator
Gyorgy Paragh, MD
PRINCIPAL INVESTIGATOR
Roswell Park
Frequently Asked Questions
Who can join the NCT07182240 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Basal Cell Carcinoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07182240 currently recruiting?
Yes, NCT07182240 is actively recruiting participants. Contact the research team at askrpc@Roswellpark.org for enrollment information.
Where is the NCT07182240 trial being conducted?
This trial is being conducted at Buffalo, United States.
Who is sponsoring the NCT07182240 clinical trial?
NCT07182240 is sponsored by Roswell Park Cancer Institute. The principal investigator is Gyorgy Paragh, MD at Roswell Park. The trial plans to enroll 60 participants.