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Recruiting NCT05566483

NCT05566483 Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

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Clinical Trial Summary
NCT ID NCT05566483
Status Recruiting
Phase
Sponsor University of Colorado, Denver
Condition Post-acute Sequelae of SARS-CoV-2 Infection
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2023-03-01
Primary Completion 2027-10-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Exercise

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 30 participants in total. It began in 2023-03-01 with a primary completion date of 2027-10-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The primary objectives of this study are to determine whether exercise training is an effective strategy for treatment of Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.

Eligibility Criteria

Inclusion Criteria: * Adults ≥18 years with documented history of COVID-19 infection and symptoms consistent with Long COVID lasting \>12 weeks after diagnosis. Exclusion Criteria: * History of cardiovascular/pulmonary disease prior to infection * COVID-related myocardial injury such as evidence of myocarditis * Deep vein thrombosis/pulmonary embolism following COVID-19 infection * Exercise intolerance resulting from conditions that are not related to cardiorespiratory or autonomic factors (e.g. osteoarthritis or other musculoskeletal diseases); * Dependency of supplemental oxygen following COVID infection due to cardiovascular and/or pulmonary complications following acute COVID infection

Contact & Investigator

Central Contact

William K Cornwell, III, MD

✉ william.cornwell@cuanschutz.edu

📞 303-724-2085

Frequently Asked Questions

Who can join the NCT05566483 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Post-acute Sequelae of SARS-CoV-2 Infection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05566483 currently recruiting?

Yes, NCT05566483 is actively recruiting participants. Contact the research team at william.cornwell@cuanschutz.edu for enrollment information.

Where is the NCT05566483 trial being conducted?

This trial is being conducted at Aurora, United States.

Who is sponsoring the NCT05566483 clinical trial?

NCT05566483 is sponsored by University of Colorado, Denver. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology