NCT07081269 Physical Fitness and Hot Executive Function in Alzheimer's Risk
| NCT ID | NCT07081269 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Taiwan Normal University |
| Condition | Executive Function (Cognition) |
| Study Type | OBSERVATIONAL |
| Enrollment | 240 participants |
| Start Date | 2025-01-10 |
| Primary Completion | 2027-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 240 participants in total. It began in 2025-01-10 with a primary completion date of 2027-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This 18-month study tracks how physical fitness relates to executive function in older adults, aiming to determine if fitness improvements predict better cognitive performance. Participants complete assessments at baseline and 18 months, including cardiorespiratory fitness (YMCA bike test), muscle strength (chest and leg press tests), and executive function (computer tasks with brain activity recording via EEG). Additional measures include physical activity questionnaires, cognitive screening (MMSE), memory tests (digit span), demographics (age, sex, education), and blood tests for APOE ε4 gene status. No exercise program will be provided, allowing observation of natural fitness-cognition relationships in daily life.
Eligibility Criteria
Inclusion Criteria: * Age 50-70. * Able to engage in fitness testing. * Normal vision or corrected-to-normal vision. Exclusion Criteria: * Suffering from cardiopulmonary-related diseases. * Suffering from cognitive, neurological or psychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, depression, schizophrenia, etc.). * Suffering from infectious diseases (e.g., hepatitis, human immunodeficiency virus or Creutzfeldt-Jakob disease). * Having a history of drug or alcohol abuse. * Having colour vision deficiency (e.g., colour blindness). * Having a family history of aneurysm. * Taking medications that affect brain function.
Contact & Investigator
Yu-Kai Chang, PhD
STUDY DIRECTOR
National Taiwan Normal University
Frequently Asked Questions
Who can join the NCT07081269 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 70 Years, studying Executive Function (Cognition). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07081269 currently recruiting?
Yes, NCT07081269 is actively recruiting participants. Contact the research team at cchu042@yahoo.com for enrollment information.
Where is the NCT07081269 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT07081269 clinical trial?
NCT07081269 is sponsored by National Taiwan Normal University. The principal investigator is Yu-Kai Chang, PhD at National Taiwan Normal University. The trial plans to enroll 240 participants.