NCT07546539 Photobiomodulation in Chronic Fatigue Syndrome
| NCT ID | NCT07546539 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Lahore |
| Condition | Chronic Fatigue Syndrome (CFS) |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-06-15 |
| Primary Completion | 2026-07-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2026-06-15 with a primary completion date of 2026-07-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to evaluate whether photobiomodulation therapy (low-level laser therapy) can reduce fatigue and improve quality of life in patients with chronic fatigue syndrome (CFS). The study will include adults aged 18-60 years diagnosed with chronic fatigue syndrome. The main questions it aims to answer are: Does photobiomodulation therapy significantly reduce fatigue levels as measured by the Fatigue Severity Scale (FSS) and Multidimensional Fatigue Inventory (MFI-20)? Does photobiomodulation therapy improve pain, functional capacity, sleep quality, and psychological well-being in patients with chronic fatigue syndrome? Researchers will compare the low-level laser therapy group with a placebo (sham laser) group to determine whether photobiomodulation therapy leads to greater improvements in fatigue, pain, and overall quality of life. Participants will: Receive either active low-level laser therapy or placebo treatment three times per week for eight weeks Undergo assessments of fatigue, pain, functional capacity, quality of life, sleep quality, and psychological well-being at baseline and follow-up intervals (3, 6, and 12 months)
Eligibility Criteria
Inclusion Criteria * Age 18-60 years * Diagnosis of a CFS according to the 2015 Institute of Medicine criteria * Fatigue Severity Scale (FSS) score ≥ 4 * Ability to understand study procedures and provide informed consent Exclusion Criteria * Comorbid psychiatric conditions (e.g., major depression, schizophrenia) * Current use of corticosteroids or immunomodulators * Known photosensitivity or dermatologic contraindications to LLLT * Participation in structured exercise programs more than twice weekly * Diagnosed malignancy or active infection -Not willing to be the part of study -
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07546539 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Chronic Fatigue Syndrome (CFS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07546539 currently recruiting?
Yes, NCT07546539 is actively recruiting participants. Contact the research team at aadilamirali@hotmail.com for enrollment information.
Where is the NCT07546539 trial being conducted?
This trial is being conducted at Larkana, Pakistan.
Who is sponsoring the NCT07546539 clinical trial?
NCT07546539 is sponsored by University of Lahore. The trial plans to enroll 40 participants.