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Recruiting NCT03731000

NCT03731000 PHIL® Embolic System Pediatric IDE

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Clinical Trial Summary
NCT ID NCT03731000
Status Recruiting
Phase
Sponsor Alejandro Berenstein
Condition Arterio-venous Fistula
Study Type INTERVENTIONAL
Enrollment 15 participants
Start Date 2019-04-16
Primary Completion 2027-12

Trial Parameters

Condition Arterio-venous Fistula
Sponsor Alejandro Berenstein
Study Type INTERVENTIONAL
Phase N/A
Enrollment 15
Sex ALL
Min Age N/A
Max Age 21 Years
Start Date 2019-04-16
Completion 2027-12
Interventions
PHIL® device

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Brief Summary

The purpose of this study is to collect information about how the PHIL® Embolic System works in the treatment of intracranial dural arteriovenous fistulas. Data collected in this study will be used to evaluate the safety and probable benefits in treating DAVFs. The PHIL® Embolic System is a Humanitarian Use Device (HUD). The U.S. Food and Drug Administration (FDA) approved the use of the PHIL Embolic System as a HUD in June 2016.

Eligibility Criteria

Inclusion Criteria: * Subject is \<22 years of age * Subject and legally authorized representative are willing and capable of complying with all study protocol requirements, including specified follow-up period. * Subject's legally authorized representative(s) must sign and date an IRB approved written informed consent prior to initiation of any study procedure * Subject has an intracranial dAVF that is deemed appropriate for embolization with PHIL without significantly increased risk to collateral or adjacent territories, OR subject has been previously treated with other embolic materials for dAVF. Exclusion Criteria: * Subject presents with an intracranial mass or is currently undergoing radiation therapy for carcinoma or sarcoma of the head or neck region * Subject has known allergies to DMSO (dimethyl sulfoxide), iodine or heparin. * Subject with a history of life threatening allergy to contrast media (unless treatment for allergy is tolerated). * Female subject is currently pregna

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