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Recruiting Phase 2 NCT01297400

NCT01297400 Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

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Clinical Trial Summary
NCT ID NCT01297400
Status Recruiting
Phase Phase 2
Sponsor Skingenix, Inc.
Condition Burns
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2022-03-11
Primary Completion 2026-12-31

Trial Parameters

Condition Burns
Sponsor Skingenix, Inc.
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 60
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2022-03-11
Completion 2026-12-31
Interventions
Investigational Drug, MW-IIISilvadene® Cream 1% [Silver Sulfadiazine]

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Brief Summary

To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" (≥95% re-epithelialization) of a partial thickness target thermal burn.

Eligibility Criteria

Inclusion Criteria: 1. Adults, 18 years of age or older on the day of signing the informed consent. 2. Thermal Burns not exceeding a total body surface area (TBSA) OF 25%, with at least one partial thickness burn of 0.5% TBSA or greater. If full thickness burn(s) are present at screening, the total full thickness burn area shall not exceed 10% TBSA. Note: TBSA excludes areas of superficial (first degree) burns. 3. Able and willing to give informed consent and comply with study procedures. Exclusion Criteria: 1. Any burn that at screening is: 1. infected. 2. circumferential or deemed, in the judgment of the investigator, at high risk for developing compartment syndrome. 3. partial thickness that is likely, in the judgment of the Investigator, to require grafting within 72 hours, or other non-protocol intervention. 2. Severe inhalation injury or other significant non-burn trauma.

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