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Recruiting NCT03593408

NCT03593408 Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

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Clinical Trial Summary
NCT ID NCT03593408
Status Recruiting
Phase
Sponsor Boston Children's Hospital
Condition Drug Effect
Study Type OBSERVATIONAL
Enrollment 20 participants
Start Date 2019-02-08
Primary Completion 2026-08-01

Eligibility & Interventions

Sex All sexes
Min Age 0 Days
Max Age 17 Years
Study Type OBSERVATIONAL
Interventions
DexmedetomidineFentanylMidazolam

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 20 participants in total. It began in 2019-02-08 with a primary completion date of 2026-08-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will measure plasma concentrations of dexmedetomidine, fentanyl, morphine and midazolam in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to understand the pharmacokinetics of these drugs in this setting.

Eligibility Criteria

Inclusion Criteria: * supported on ECMO * receiving one or a combination of the following drugs dexmedetomidine, fentanyl, midazolam or morphine as part of sedation management Exclusion Criteria: -none

Contact & Investigator

Central Contact

Viviane Nasr, MD

✉ viviane.nasr@childrens.harvard.edu

📞 617-355-6225

Principal Investigator

Viviane Nasr, MD

PRINCIPAL INVESTIGATOR

Boston Children's Hospital

Frequently Asked Questions

Who can join the NCT03593408 clinical trial?

This trial is open to participants of all sexes, aged 0 Days or older, up to 17 Years, studying Drug Effect. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03593408 currently recruiting?

Yes, NCT03593408 is actively recruiting participants. Contact the research team at viviane.nasr@childrens.harvard.edu for enrollment information.

Where is the NCT03593408 trial being conducted?

This trial is being conducted at Boston, United States.

Who is sponsoring the NCT03593408 clinical trial?

NCT03593408 is sponsored by Boston Children's Hospital. The principal investigator is Viviane Nasr, MD at Boston Children's Hospital. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology