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Recruiting EARLY_Phase 1 NCT07033845
NCT07033845 Pharmacokinetic Study of Topical Phenylephrine
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Plain-language summary for patients
| NCT ID | NCT07033845 |
| Status | Recruiting |
| Phase | EARLY_Phase 1 |
| Sponsor | Applied Biology, Inc. |
| Condition | Chemotherapy Induced Alopecia |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2025-06-30 |
| Primary Completion | 2025-10-19 |
Trial Parameters
Condition Chemotherapy Induced Alopecia
Sponsor Applied Biology, Inc.
Study Type INTERVENTIONAL
Phase EARLY_Phase 1
Enrollment 24
Sex FEMALE
Min Age 18 Years
Max Age 55 Years
Start Date 2025-06-30
Completion 2025-10-19
All Conditions
Interventions
Phenylephrine
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Brief Summary
Pharmacokinetic Study of Topical Phenylephrine
Eligibility Criteria
Inclusion Criteria: * Healthy females, age 18-55 * BMI: 18-30 kg/m² * Fitzpatrick Skin Types I-IV (to standardize absorption risk) * Scalp free from irritation, dermatologic disease, or damage * Able to refrain from using other topical scalp products Exclusion Criteria: * History of cardiovascular disease, hypertension, or arrhythmia * Scalp infections, wounds, or significant hair loss * Recent use of medications that interfere with CYP enzymes or adrenergic systems * Known sensitivity to phenylephrine or ethanol * Positive drug screen or abnormal ECG at screening
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