NCT07898137 Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Brown Rice
| NCT ID | NCT07898137 |
| Status | Recruiting |
| Phase | — |
| Sponsor | North Carolina Agriculture & Technical State University |
| Condition | Healthy Adult Males |
| Study Type | INTERVENTIONAL |
| Enrollment | 16 participants |
| Start Date | 2027-01-15 |
| Primary Completion | 2027-05-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 16 participants in total. It began in 2027-01-15 with a primary completion date of 2027-05-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research study is to identify biomarkers (measurable signs). in the body like substances in blood or urine) of whole-grain (WG) brown rice intake following an acute exposure in a pharmacokinetic (how the body absorbs, processes, and gets rid of a substance or ingredient) feeding study. In this aim, investigators will conduct a randomized crossover acute pharmacokinetic study of brown rice. Investigators will then use a targeted metabolomics approach to identify the exposure markers of brown rice intake, further develop analytical methods to study its pharmacokinetics, build an in-house WG metabolite database, and use an untargeted metabolomics approach to investigate postprandial biomarkers of brown rice intake. At the completion of this study, the expectation is that investigators will identify brown rice phytochemicals and its metabolites as objective biomarkers of total and individual WGs that are commonly consumed by Americans.
Eligibility Criteria
Inclusion Criteria: * Adults aged 25-70 years * Body mass index (BMI) between 18 and 30 kg/m² * Able to read, speak, and understand English * No known allergy or intolerance to the test foods * Normal blood and urine biochemical parameters * No antibiotic use within the past 6 months * Willing and able to comply with all study procedures, including dietary restrictions throughout the study period * No medical conditions or lifestyle factors that, in the opinion of the investigators, would interfere with the study objectives Exclusion Criteria: * Active disease, including gout, heart disease, peripheral vascular disease, kidney disease, liver disease, cancer, diabetes, gastrointestinal disorders, or endocrine disorders that may interfere with the study * Current smoker or use of tobacco products * Unwilling or unable to comply with the required dietary restrictions during the study period
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07898137 clinical trial?
This trial is open to participants of all sexes, aged 25 Years or older, up to 70 Years, studying Healthy Adult Males. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07898137 currently recruiting?
Yes, NCT07898137 is actively recruiting participants. Contact the research team at ssang@ncat.edu for enrollment information.
Where is the NCT07898137 trial being conducted?
This trial is being conducted at Kannapolis, United States.
Who is sponsoring the NCT07898137 clinical trial?
NCT07898137 is sponsored by North Carolina Agriculture & Technical State University. The trial plans to enroll 16 participants.