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Recruiting NCT06943586

NCT06943586 Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

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Clinical Trial Summary
NCT ID NCT06943586
Status Recruiting
Phase
Sponsor University of Alabama at Birmingham
Condition Stroke
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2025-04-09
Primary Completion 2028-04-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 89 Years
Study Type INTERVENTIONAL
Interventions
CYP2C19 Genotype Guided DAPT (dual antiplatelet therapy)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2025-04-09 with a primary completion date of 2028-04-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this research study is to explore whether genetic testing can offer a personalized and timely approach to assist physicians in making more informed medication decisions for stroke or high-risk transient ischemic attack (TIA) patients during their hospital stay.

Eligibility Criteria

Inclusion Criteria: * Patients 18-89 years of age * admitted to University of Alabama at Birmingham (UAB) main hospital with symptoms or signs of minor ischemic stroke, or high risk TIA * eligible to receive dual antiplatelet load (presented to the hospital within 66 hours of last known well) Exclusion Criteria: * diagnosis of atrial fibrillation, valvular heart disease, index stroke due to known hypercoagulability (subset of other determined etiology) or large vessel disease (culprit vessel stenosis of ≥50%) * prescribed anticoagulation prior to stroke * treated with intravenous thrombolysis * treated with mechanical thrombectomy * missing NIH Stroke Scale score

Contact & Investigator

Central Contact

Ekaterina Bakradze, MD

✉ ebakradze@uabmc.edu

📞 205-975-8569

Principal Investigator

Ekaterina Bakradze, MD

PRINCIPAL INVESTIGATOR

University of Alabama at Birmingham

Frequently Asked Questions

Who can join the NCT06943586 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 89 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06943586 currently recruiting?

Yes, NCT06943586 is actively recruiting participants. Contact the research team at ebakradze@uabmc.edu for enrollment information.

Where is the NCT06943586 trial being conducted?

This trial is being conducted at Birmingham, United States.

Who is sponsoring the NCT06943586 clinical trial?

NCT06943586 is sponsored by University of Alabama at Birmingham. The principal investigator is Ekaterina Bakradze, MD at University of Alabama at Birmingham. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology