NCT05533528 Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment
| NCT ID | NCT05533528 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universidad de Murcia |
| Condition | Periodontal Pocket |
| Study Type | INTERVENTIONAL |
| Enrollment | 25 participants |
| Start Date | 2022-05-03 |
| Primary Completion | 2026-12-22 |
Trial Parameters
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
Brief Summary
The objective of this study will be to evaluate a new protocol for the surgical treatment of periodontal disease with two novelties: to make a single incision in the midline of the interproximal area to respect the vascular supply and preserve the granulation tissue with regenerative potential. The investigators will carry out a controlled and randomized clinical trial with a control group (n=25; modified Kirkland flap) and a test group (n=25; experimental surgical protocol: incision in the mid-interproximal area of the papilla and preservation of the granulation tissue). Clinical parameters will be taken at the time of surgery and 12 months follow-up: bleeding on probing (BoP), clinical attachment level (CAL), residual probing depth (rPD),Probing pocket depth reduction (PPDr), recession (REC), interproximal gingival recession (iGR), width of keratinized gingiva (KT), gain of supra-alveolar clinical attachment (SUPRA-AG), early wound healing index (EHI).
Eligibility Criteria
Inclusion Criteria: * Stage III or IV periodontitis, including all grades. * Unresolved deep pockets (probing pocket depth \[PPD\] \>5 mm + BoP) 4 to 6 weeks after non-surgical treatment. * Interproximal plaque index \<35% maintained during periodontal treatment and maintenance. * Adherence to periodontal maintenance appointments. Exclusion Criteria: * Systemic disease contraindicating periodontal surgery. * Teeth with incorrect endodontic treatment or restoration. * Stage I or II periodontitis.