NCT05533528 Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment
| NCT ID | NCT05533528 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universidad de Murcia |
| Condition | Periodontal Pocket |
| Study Type | INTERVENTIONAL |
| Enrollment | 25 participants |
| Start Date | 2022-05-03 |
| Primary Completion | 2026-12-22 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 25 participants in total. It began in 2022-05-03 with a primary completion date of 2026-12-22.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of this study will be to evaluate a new protocol for the surgical treatment of periodontal disease with two novelties: to make a single incision in the midline of the interproximal area to respect the vascular supply and preserve the granulation tissue with regenerative potential. The investigators will carry out a controlled and randomized clinical trial with a control group (n=25; modified Kirkland flap) and a test group (n=25; experimental surgical protocol: incision in the mid-interproximal area of the papilla and preservation of the granulation tissue). Clinical parameters will be taken at the time of surgery and 12 months follow-up: bleeding on probing (BoP), clinical attachment level (CAL), residual probing depth (rPD),Probing pocket depth reduction (PPDr), recession (REC), interproximal gingival recession (iGR), width of keratinized gingiva (KT), gain of supra-alveolar clinical attachment (SUPRA-AG), early wound healing index (EHI).
Eligibility Criteria
Inclusion Criteria: * Stage III or IV periodontitis, including all grades. * Unresolved deep pockets (probing pocket depth \[PPD\] \>5 mm + BoP) 4 to 6 weeks after non-surgical treatment. * Interproximal plaque index \<35% maintained during periodontal treatment and maintenance. * Adherence to periodontal maintenance appointments. Exclusion Criteria: * Systemic disease contraindicating periodontal surgery. * Teeth with incorrect endodontic treatment or restoration. * Stage I or II periodontitis.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05533528 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Periodontal Pocket. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05533528 currently recruiting?
Yes, NCT05533528 is actively recruiting participants. Contact the research team at ajortiz@um.es for enrollment information.
Where is the NCT05533528 trial being conducted?
This trial is being conducted at Murcia, Spain.
Who is sponsoring the NCT05533528 clinical trial?
NCT05533528 is sponsored by Universidad de Murcia. The trial plans to enroll 25 participants.