Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest
Trial Parameters
Brief Summary
Out-of-hospital cardiac arrest (OHCA) has multiple etiologies. In the absence of ST-elevation myocardial infarction, percutaneous coronary intervention (PCI) is delayed. This study aims to determine the diagnostic accuracy of Coronary Calcium Score (CCS) and Coronary CT Angiogram (CCTA) to rule out a coronary artery disease (CAD) in the first days after an OHCA.
Eligibility Criteria
Inclusion criteria : * Patients hospitalized in intensive care unit after a resuscitated out-of-hospital cardiac arrest * No obvious cause for sudden death on anamnestic information, CT brain and CT pulmonary angiogram. * Absence of ST elevation myocardial infarction Non-inclusion criteria : * In-hospital cardiac arrest * Refractory cardiac arrest * Indication of immediate coronary angiography * ST-elevation myocardial infarction or unknown left bundle branch block * Dynamic or presumably new contiguous ST/T-segment changes * Cardiogenic shock * Life-threatening arrhythmias * Coronary artery bypass graft * Pregnancy * Multiple organ failure syndrome * Know severe chronic kidney disease (GFR \<30mL/min/1,73m²) Exclusion criteria : * During the Coronary computerized tomographic angiogram : * Haemodynamic instability requiring high dose of vasopressors (\>1µg/kg/min of Norepinephrine) * Non sinusal cardiac rhythm * KDIGO 1 Acute kidney injury