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Recruiting NCT05867173

Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces

◆ AI Clinical Summary
Plain-language summary for patients

Trial Parameters

Condition Deafness
Sponsor Massachusetts Eye and Ear Infirmary
Study Type INTERVENTIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age 3 Months
Max Age N/A
Start Date 2022-09-16
Completion 2027-03-31
Interventions
Experimental Speech Processing Strategy

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Brief Summary

Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and adults who receive them. The main goals of this project are: i) to improve our understanding of how cochlear implants affect the developing auditory system, ii) apply that knowledge to test new methods for programming children and adults, and iii) to study how long it takes listeners to adapt to new cochlear implant programs over the short- and long-term. The results will improve our understanding of how the deafened auditory system develops with cochlear implant stimulation and advance clinical practice to improve hearing outcomes in cochlear implant listeners.

Eligibility Criteria

Inclusion Criteria: Research Subjects with a Cochlear Implant ADULTS Inclusion Criteria * Adult at least 18 years old * Native speakers of American English * Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer), Cochlear, or MED-EL CHILDREN Inclusion Criteria * Children at least 3 months old * Native speakers of American English * Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer), Cochlear, or MED-EL * For both children and adults with a cochlear implant, some study criteria might pertain to a subset of subjects, such as a specific age at which the subjects developed a hearing loss, or was implanted. Exclusion Criteria: Exclusion for all Cochlear Implant Subjects: * Inability to provide informed consent * Does not meet the inclusion criteria for a specific study protocol, such as age of onset of hearing loss, age of cochlear implantation, duration of deafness, number of active electrodes in the cochlear implant de

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