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Recruiting NCT07239817

NCT07239817 PENG Block + LIA For Endoprosthesis Surgery

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Clinical Trial Summary
NCT ID NCT07239817
Status Recruiting
Phase
Sponsor ASST Gaetano Pini-CTO
Condition Hip Fractures
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2025-12-09
Primary Completion 2026-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Pericapsular Nerve Group Blocks with Local Infiltration Analgesiaspinal anesthesia

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2025-12-09 with a primary completion date of 2026-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery. The main questions it aims to answer are: * Is the new local anesthesia technique as effective as standard spinal anesthesia in managing pain during the first two days after surgery? * Does the new technique allow participants to move their leg sooner after the operation? Researchers will compare the new local anesthesia technique (numbing medicine injected directly around the hip joint) to standard spinal anesthesia (a numbing injection in the back) to see if the new technique works just as well for pain control while possibly causing fewer side effects like nausea. Participants who join this study will be randomly placed into one of two groups. One group will receive the standard spinal anesthesia before their surgery. The other group will receive the new local anesthesia technique before their surgery. After the operation, researchers will track the amount of extra pain medicine each participant uses and will check their ability to move their hip, knee, and foot.

Eligibility Criteria

Inclusion Criteria: * Provision of signed and dated informed consent form. * Scheduled for hip endoprosthesis surgery for femoral fracture with an anterior approach. * Age 18 years or older. * Willing and able to comply with the study protocol. Exclusion Criteria: * Failure to provide informed consent. * Age less than 18 years. * Known allergy to local anesthetics or other medications used in the protocol. * Presence of infection at the planned injection site. * Pre-existing hip prosthesis or prior major surgery on the same hip (e.g., revision surgery). * ASA physical status class \> IV. * Administration of intraoperative opiates or conversion to general anesthesia.

Contact & Investigator

Central Contact

Romualdo Del Buono, MD

✉ romualdo.delbuono@asst-pini-cto.it

📞 +39 02 5829 6592

Principal Investigator

Romualdo Del Buono, MD

PRINCIPAL INVESTIGATOR

Unit of Anesthesia, Intensive Care and Pain Management, ASST Gaetano Pini, Milan, Italy;

Frequently Asked Questions

Who can join the NCT07239817 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Hip Fractures. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07239817 currently recruiting?

Yes, NCT07239817 is actively recruiting participants. Contact the research team at romualdo.delbuono@asst-pini-cto.it for enrollment information.

Where is the NCT07239817 trial being conducted?

This trial is being conducted at Milan, Italy.

Who is sponsoring the NCT07239817 clinical trial?

NCT07239817 is sponsored by ASST Gaetano Pini-CTO. The principal investigator is Romualdo Del Buono, MD at Unit of Anesthesia, Intensive Care and Pain Management, ASST Gaetano Pini, Milan, Italy;. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology