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Recruiting NCT05973838

NCT05973838 Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

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Clinical Trial Summary
NCT ID NCT05973838
Status Recruiting
Phase
Sponsor University of Maryland, College Park
Condition Polysubstance Addiction
Study Type INTERVENTIONAL
Enrollment 160 participants
Start Date 2023-06-15
Primary Completion 2027-07-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Peer-Delivered Behavioral Activation ("Peer Activate")

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 160 participants in total. It began in 2023-06-15 with a primary completion date of 2027-07-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) and reduce polysubstance use among patients with OUD and polysubstance use in underserved areas. The intervention is based on behavioral activation (BA) and is specifically designed to be implemented by a trained peer recovery specialist. In this hybrid, Type-1 effectiveness-implementation randomized controlled trial (RCT), the investigators will evaluate the effectiveness and implementation of Peer Activate vs. treatment as usual (TAU) over twelve months.

Eligibility Criteria

Inclusion Criteria: Patient participants in the RCT must be 18 or older; receive OUD treatment as part of the telemedicine program; and exhibit polysubstance use within the past three-months (i.e., use of one or more non-prescribed substances (excluding opioids and/or tobacco) by urine toxicology or self-report. Exclusion Criteria: * Demonstrating active, unstable or untreated psychiatric symptoms, including mania and/or psychosis that would interfere with study participation * Inability to understand the study and provide informed consent in English

Contact & Investigator

Central Contact

Morgan S Anvari, BA

✉ manvari@umd.edu

📞 3014055095

Principal Investigator

Jessica F Magidson, PhD

PRINCIPAL INVESTIGATOR

University of Maryland, College Park

Frequently Asked Questions

Who can join the NCT05973838 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Polysubstance Addiction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05973838 currently recruiting?

Yes, NCT05973838 is actively recruiting participants. Contact the research team at manvari@umd.edu for enrollment information.

Where is the NCT05973838 trial being conducted?

This trial is being conducted at Washington D.C., United States, Baltimore, United States, College Park, United States, Denton, United States.

Who is sponsoring the NCT05973838 clinical trial?

NCT05973838 is sponsored by University of Maryland, College Park. The principal investigator is Jessica F Magidson, PhD at University of Maryland, College Park. The trial plans to enroll 160 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology