NCT07533188 Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types
| NCT ID | NCT07533188 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Singapore General Hospital |
| Condition | Knee Osteoarthritis |
| Study Type | INTERVENTIONAL |
| Enrollment | 240 participants |
| Start Date | 2025-10-14 |
| Primary Completion | 2027-10-14 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 240 participants in total. It began in 2025-10-14 with a primary completion date of 2027-10-14.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate patient outcomes following robotic-assisted total knee arthroplasty using the VELYS system. Patients undergoing surgery will receive either kinematic alignment or functional alignment as determined by the operating surgeon as part of routine clinical care. Within each surgical technique group, patients will be randomly assigned to receive different implant insert types (medial stabilised or cruciate retaining) using a REDCap-based randomisation process. Patient-reported outcome measures will be collected before surgery and at follow-up time points after surgery to assess clinical outcomes.
Eligibility Criteria
\*Inclusion Criteria:\* * Patients undergoing robotic-assisted total knee arthroplasty using the VELYS system * Diagnosis of knee osteoarthritis requiring surgical intervention * Able to provide informed consent * Willing to complete patient-reported outcome measures \*\*Exclusion Criteria:\*\* * Patients undergoing revision knee arthroplasty * Presence of active infection * Inability to comply with follow-up assessments * Severe co-morbidities that may affect surgical outcomes or participation in the study
Frequently Asked Questions
Who can join the NCT07533188 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Knee Osteoarthritis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07533188 currently recruiting?
Yes, NCT07533188 is actively recruiting participants. Visit ClinicalTrials.gov or contact Singapore General Hospital to inquire about joining.
Where is the NCT07533188 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT07533188 clinical trial?
NCT07533188 is sponsored by Singapore General Hospital. The trial plans to enroll 240 participants.