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Recruiting NCT03979170

NCT03979170 Patient-derived Organoids of Lung Cancer to Test Drug Response

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Clinical Trial Summary
NCT ID NCT03979170
Status Recruiting
Phase
Sponsor University Hospital, Geneva
Condition Lung Cancer
Study Type OBSERVATIONAL
Enrollment 50 participants
Start Date 2019-04-01
Primary Completion 2026-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Lung tumor resection

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 50 participants in total. It began in 2019-04-01 with a primary completion date of 2026-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a single center, single arm, open and exploratory clinical study, with 50 cases planned for a period of 3 years. The purpose of this study is to evaluate the consistency and accuracy of a Patient-Derived Organoid (PDO) Model of lung cancer to predict the clinical efficacy of anti-cancer drugs, in order to predict the best chemotherapy regimen for each given patient.

Eligibility Criteria

Inclusion Criteria: * Histologically proven lung cancer * Age ≥ 18 * Written informed and signed consent * Accessible to biopsy and/or surgery sample of metastasis and/or primitive tumour Exclusion Criteria: * Less than 18 years of age * Not able to give informed consent (language, intellectual capacities, etc.) * Not accessible to biopsy and/or surgery sample * Not enough lung tissue for a histological analysis or the remaining lung tissue is not enough to perform a routine pathological analysis.

Contact & Investigator

Central Contact

Veronique SERRE-BEINIER, PhD

✉ veronique.serre-beinier@hcuge.ch

📞 (0)223795107

Frequently Asked Questions

Who can join the NCT03979170 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03979170 currently recruiting?

Yes, NCT03979170 is actively recruiting participants. Contact the research team at veronique.serre-beinier@hcuge.ch for enrollment information.

Where is the NCT03979170 trial being conducted?

This trial is being conducted at Geneva, Switzerland.

Who is sponsoring the NCT03979170 clinical trial?

NCT03979170 is sponsored by University Hospital, Geneva. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology