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Recruiting NCT07156422

Pathophysiological Study of the Sensitive Scalp

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Plain-language summary for patients

Trial Parameters

Condition Sensitive Scalp
Sponsor University Hospital, Brest
Study Type INTERVENTIONAL
Phase N/A
Enrollment 40
Sex FEMALE
Min Age 18 Years
Max Age N/A
Start Date 2026-01-28
Completion 2027-01
Interventions
A scalp biopsy using a 4 mm punch in the retroauricular hair zonea general health questionnaireQuestionnaires concerning their sensitive scalp

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Brief Summary

Sensitive skin is defined as a syndrome manifested by the occurrence of unpleasant sensations (tingling, burning, pain, pins and needles) in response to stimuli that should not normally cause them. These unpleasant sensations cannot be explained by lesions attributable to a specific skin disease. Sensitive skin can affect different parts of the body. The scalp is a site that is often affected, with specificity linked in particular to the presence of hair and different triggering factors (styling habits, wearing of head coverings, application of cosmetics to the scalp, etc.). Sensitive scalp affects around half the population, and can have an impact on the quality of life of sufferers, particularly those whose symptoms are very intense. Women are more likely than men to have a sensitive scalp, so in order to have a more homogenous study population, we chose to include 40 women. The pathophysiology of sensitive skin is imperfectly understood, and studies specific to the sensitive scalp are very rare. However, the pathophysiology of the sensitive scalp could be different because it is a hairy area, more innervated, and less exposed to environmental factors.

Eligibility Criteria

Inclusion Criteria: * Adult women without dermatosis * Collection of free and informed consent * patient affiliated to a social security scheme For the control group: Sensiscalp score = 0/20 Sensitive scalp group: Sensiscalp score ≥ 3/20 with pruritus sensation ≥ 2/20 Exclusion Criteria: * Refusal to take part in the study * Dermatosis of the scalp (psoriasis, seborrhoeic dermatitis, etc.) * Pregnant and breast-feeding women * Women under legal protection (guardianship, curatorship)

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